In addition, several departments in the College of Arts and Sciences offer undergraduate majors leading to Ohio teaching licenses. Students wishing to pursue a teaching license in one of these areas must fulfill all the requirements for their primary major and declare teacher education as a second major, following the appropriate course sequences that lead to licensure. The teacher licensure areas are: 1) Adolescent to Young Adult (grades 7-12) in Integrated Language Arts (English major), Integrated Social Studies (history major), Integrated Mathematics (mathematics major), Life Science (biology major), or Physical Science (chemistry and/or physics major); and 2) Multi-Age (grades preK-12) in French, Spanish, or Latin.

Teacher licensure programs at Case Western Reserve University lead to teaching licenses and are approved by the Ohio Department of Education and the Ohio Board of Regents. The Teacher Education Unit at CWRU is nationally accredited by the Teacher Education Accreditation Council (TEAC), which is part of the Council for the Accreditation of Educator Preparation (CAEP). In addition, the National Association of Schools of Music (NASM) accredits the Music Education Program.