As a response to Barry University's commitment to theological education in the Southeast region of the United States and the growing Hispanic population of that region, courses are offered through a collaborative effort with the Southeast Pastoral Institute (SEPI), located at 7700 SW 56 Street, Miami, FL 33155. SEPI is an educational branch of the Southeast Regional Office for Hispanic affairs, Region V and XIV of the National Conference of Catholic Bishops.

The purpose of the Master of Arts in Pastoral Ministry for Hispanics is to prepare lay ecclesial ministers and to provide focused theological reflection on Hispanic cultural contexts and social realities currently challenging the Roman Catholic Church and other Christian communities. All coursework offered in the program is conducted in Spanish.